Learn how to use this product Several human degenerative diseases result from protein misfolding and aggregation. The prototype central nervous system protein pathology is CJD, in which neuronal prion protein (PrP) with high α-helical content switches into a stable structure rich in β-pleated sheets in a self-catalyzing process that eventually causes a plethora of neurologic and psychiatric symptoms.

Anti-bovine prion protein mab 4F7 specifically binds to bovine prion protein aa YY…MHRY…YY. Purified, in PBS w/o additives, frozen at -20°C, 12 months shelf life. ELISA, WB, IHC, IF