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The X-CLARITY™ Mounting Solution is a refractive index matching solution (RIMS) derived from the formula introduced by Yang et al. (Cell 158, 945–958 (2014)). The X-CLARITY™ Mounting Solution's refractive index (RI) is 1.460 at 25°C and is stable over a wide temperature range. This solution minimizes photobleaching and preserves fluorescence signals, rendering it an ideal solution for clarified and fluorescence-labeled tissue samples. The X-CLARITY™ Mounting Solution is also available as a value pack (10 X 25 mL) (LB C13102).