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Anti-human prion protein 5C4 monoclonal antibody - 100 µg
Learn how to use this product Several human degenerative diseases resulted from misfolding and aggregation of proteins. The prototype central nervous system protein pathology is CJD, in which neuronal prion protein (PrP) with high α-helical content switches into a stable structure rich in β-pleated sheets in a self-catalyzing process that eventually causes a plethora of neurologic and psychiatric symptoms.
Anti-human prion protein mab 5C4 specifically binds to bovine prion protein aa PPQGGGGWGQPH (octarepeats).
Purified, in PBS w/o additives, frozen at -20°C, 12 months shelf life. ELISA, WB, IHC, IF