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Anti-bovine prion protein 3B8 monoclonal antibody - 100 µg
Learn how to use this product Several human degenerative diseases resulted from misfolding and aggregation of proteins. The prototype central nervous system protein pathology is CJD, in which neuronal prion protein (PrP) with high α-helical content switches into a stable structure rich in β-pleated sheets in a self-catalyzing process that eventually causes a plethora of neurologic and psychiatric symptoms.
Anti-bovine prion protein mab 3B8 specifically binds to the conformational epitope of bovine prion protein containing sequences GSDYEDRY and YRPVDQ.
Purified, in PBS w/o additives, frozen at -20°C, 12 months shelf life. ELISA, WB, IHC, IF